p4 stirling colour

Competences: The University of Stirling (UoS) has over 9,000 students and 2,000 staff and through the Institute of Aquaculture (IoA) is a world-renowned centre of excellence for research and teaching in Aquaculture. The IoA gained a 5 star rating in the 2001 RAE and, in the 2008 RAE, 50 and 90% of

Overall Research was rated “internationally excellent” and “internationally recognised”, respectively, with the equivalent figures for Research Environment being 62.5 and 100%, respectively. The Nutrition Group is a world-leading group in fish lipid and fatty acid metabolism and nutrition, including the application of molecular technologies and has a commercially-operated lipid analytical service.

Material resources: UOS facilities include state of the art HPLC, GC, GC-MS for detailed analyses of lipids, fatty acids, vitamins, carotenoids and pollutants, a scanning densitometer for lipid class analysis and Soxlet and Kjeldahl equipment for semi-automated proximate analyses. The cell culture lab has cooled and CO2 incubators, laminar flow hoods and microscopes. Facilities for advanced molecular studies (including transcriptomics and proteomics) include five dedicated laboratories with isotope facilities, media prep room, incubation room with orbital, rotary, and heated and cooled incubators, a dark room, and two DNA sequencers, three QPCR machines with a liquid handling robot, two microarray hybridisers and two laser microarray scanners for transcriptomic analyses, and equipment for DIGE proteomic analyses including isoelectric focussing and 2-D PAGE electrophoresis, typhoon scanner and spot-picker. The ‘omic work is supported by a Bioinformatic laboratory with multiple computer terminal stations with access to bioinformatic analyses programmes.

Role: UOS will lead WP4 (Analysis of the long-term effects) and contribute expertise and knowledge to all WPs, especially in the areas of lipid and fatty acid biochemistry and molecular biology, reproduction, endocrinology and genetics.

Staff members’ profile:

  • Prof. J. Gordon Bell has 30 years of research specialising in fish nutrition with an emphasis on lipid nutrition, PUFA and their role in health related to autooxidation. Other recent activities involve the establishment of expertise in the study of organic lipid-soluble contaminants and the importance of seafood in human nutrition.
  • Prof. Douglas R. Tocher has 30 years of research experience specialising in the biochemistry and molecular biology of fish, focussing on lipid and fatty acid metabolism and the control and regulation of gene expression. He has gained worldwide recognition for his work in investigating the molecular mechanisms of LC-PUFA synthesis in fish.
  • Dr. Herve Migaud has more than 12 years of research experience in fish physiology, reproduction, endocrinology, genetics and welfare with recent emphasis on salmonids. Currently, he is involved in studies on triploidy, smoltification and puberty at the endocrine and molecular levels, and responses to environmental, nutritional and genetic factors.

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The research leading to these results has received funding from the European Union’s Seventh Framework Programme (FP7 /2007-2013) under grant agreement no 288925. This publication reflects the views only of the author, and the European Union cannot be held responsible for any use which maybe made of the information contained therein.